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Hepatotrophic effect of cyclosporine and FK 506 is not mimicked by Rapamycin

✍ Scribed by R Chávez; N Jamieson; S Takamori; S Nivatvongs; G Pino; A Metcalfe; C Watson; D Romero; S Metcalfe

Book ID
117238431
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
82 KB
Volume
31
Category
Article
ISSN
0041-1345

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Suppression of B cell activation by cycl
Suppression of B cell activation by cyclosporin A, FK506 and rapamycin
✍ Linda S. Wicker; Robert C. Boltz Jr.; Victoria Matt; Elizabeth A. Nichols; Laure 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 722 KB

## Abstract The effects of the immunosuppressants cyclosporin A (CsA), FK506 and rapamycin have been compared using murine B cells activated with a variety of mitogens. FK506 is a macrolide antibiotic that has been recently shown to inhibit T cell activation by a mechanism that appears similar to t