TGF-beta is a potent inhibitor of EGF-induced DNA synthesis in primary rat hepatocyte cultures. Norepinephrine (NE) was shown to modulate this inhibition of DNA synthesis. It produced a five-fold increase, from 2.8 pM to 14.4 pM, in the IDSo for TGF-beta. The effect was dose-dependent and was signif
β¦ LIBER β¦
Hepatocyte conditioned medium modulates the response of primary rat hepatocyte cultures to epidermal growth factor
β Scribed by George G. Skouteris; Matthew R. Kaser
- Book ID
- 119121312
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 402 KB
- Volume
- 1095
- Category
- Article
- ISSN
- 0167-4889
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Abbreviations: TGF, transforming growth factor; EGF, epidermal growth factor; HGF, hepatocyte growth factor; [Ca'-l,, intracellular calcium concentration; I Ca2+ IL, extracellular calcium concentration. From the 'Centre de recherche clinique Andre-
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