Focusing in on P53 in hepatocellular car
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David Carbone
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Article
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1991
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John Wiley and Sons
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English
โ 366 KB
Human hepatocellular carcinomas (HCC) from patients in Qidong, an area of high incidence in China, in which both hepatitis B virus and afiatoxin B, are risk factors, were analysed for mutations in p53, a putative tumour-suppressor gene. Eight of the 16 HCC had a point mutation at the third base posi