Hepatitis C virus infection and lymphomas

✍ Scribed by Semra Paydas

• Publisher: John Wiley and Sons
• Year: 2004
• Tongue: French
• Weight: 37 KB
• Volume: 113
• Category: Article
• ISSN: 0020-7136
• DOI: 10.1002/ijc.20559

✦ Synopsis

I read with great interest the article by De Sandose et al. 1 They reported 5.9% anti-HCV prevalence in cases with NHL and the prevalence was 3.8% in controls. OR was highest (35.98) in cases with low-grade B-cell lymphomas. They concluded that HCV infection is associated with an increased risk of lymphoid neoplasms. We studied in southern Turkey HCV prevalence in 3 different studies. In our first study, anti-HCV antibody was examined in 228 cases with lymphoproliferative diseases; 26 of them (11.40%) were found to be positive, which was higher than the controls. Among these, 98 had NHL and 9 of them (11.11%) was found to be positive for anti-HCV antibody. OR for anti-HCV was 24.09. 2 In our second study, anti-HCV antibody was examined in 223 cases with NHL and it was found to be positive in 18 (8.1%). Common OR was 34.56 and corrected OR was 19.07. Among these cases, HCV-RNA was studied in 67 cases and 21 of them were found to be