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Hepatitis B virus X protein suppresses caveolin-1 expression in hepatocellular carcinoma by regulating DNA methylation

✍ Scribed by Jun Yan, Qian Lu, Jiahong Dong, Xiaowu Li, Kuansheng Ma, Lei Cai


Book ID
119897404
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
896 KB
Volume
12
Category
Article
ISSN
1471-2407

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The hepatitis B virus (HBV) X protein has been implicated as a potential trigger of the epigenetic modifications of some genes during hepatocarcinogenesis, but the underlying mechanisms remain unknown. MicroRNAs (miRNAs), which are noncoding RNAs that regulate gene expression, are involved in divers