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Hepatitis B virus genotypes, precore mutations, and basal core promoter mutations in HBV-infected Chinese patients with persistently normal alanine aminotransferase and low serum HBV-DNA levels

✍ Scribed by Shi, Ming; Zhang, Yong; Zhang, Jing; Liu, Wei; Xing, Lu

Book ID: 121773492
Publisher: SciELO
Year: 2012
Tongue: English
Weight: 131 KB
Volume: 16
Category: Article
ISSN: 1413-8670
DOI: 10.1016/S1413-8670(12)70274-X

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Spontaneous mutations of hepatitis B virus (HBV) could influence the severity of liver disease. Since the basal core promoter (BCP) and the precore (Pc) regions are important for viral replication, these regions were examined for naturally occurring mutations and were correlated with the genotype, e