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HBsAg, HBeAg and HBV DNA level changes and precore/basal core promoter mutations in the natural history of chronic hepatitis B in Indonesian patients

✍ Scribed by Turyadi, Meta Dewi Thedja, Susan Irawati Ie…


Book ID
120902135
Publisher
Springer-Verlag
Year
2013
Tongue
English
Weight
592 KB
Volume
7
Category
Article
ISSN
1936-0533

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## Abstract The A1762T and G1764A mutations in the basal core promoter (BCP) region and the G1896A mutation in the precore (PC) region of hepatitis B virus (HBV) genome are found commonly in HBeAg‐negative patients. Experiments in vitro suggest that BCP and PC mutation reduce and abolish HBeAg expr