Hepatitis B virus genetic diversity and its impact on diagnostic assays
β Scribed by F. B. Hollinger
- Book ID
- 108886064
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 393 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1352-0504
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## Abstract Hepatitis B virus (HBV) has been classified into eight genotypes, and several subgenotypes, distinctly distributed geographically. The genotypes A and D were previously reported to be predominant in India. Recent studies indicated evidence of circulation of genotype C in Eastern part of
## Abstract Hepatitis B virus (HBV) genomes have been classified into six groups, AβF, group F being the most divergent. South America has provided the smallest number of strains studied at the genome level. The only HBV strain from this region sequenced completely has been classified in group F, a
Genotype D occult hepatitis B virus (HBV) infections (OBIs) have a high frequency of amino acid substitutions in the major hydrophilic region of the small surface protein (S protein). This possibly reflects an escape mutation mechanism to evade detection by the host immune system. Mutations may also