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Hepatic uptake of organic anions affects the plasma bilirubin level in subjects with Gilbert's syndrome mutations in UGT1A1

✍ Scribed by Marcello Persico; Eliana Persico; Conny T.M. Bakker; Igino Rigato; Antonio Amoroso; Roberto Torella; Piter J. Bosma; Claudio Tiribelli; J.Donald Ostrow


Book ID
111721431
Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
163 KB
Volume
33
Category
Article
ISSN
0270-9139

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Abnormal hepatic uptake of low doses of
✍ Sandro Gentile; Marcello Persico; Claudio Tiribelli πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 497 KB

The plasma disappearance rate of sulfobromophthalein (VBsp; pmol/kg/min) was measured in 15 Gilbert's syndrome patients and 12 control subjects after intravenous injection of two different doses (0.59 and 6.90 pmol/kg) of the dye. Plasma disappearance rate was significantly reduced in Gilbert's synd