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Hepatic gene therapy: Efficient retroviral mediated gene transfer into rat hepatocytes in vivo

โœ Scribed by Tadeusz M. Kolodka; Milton Finegold; Mark A. Kay; Savio L. Woo

Book ID
112718932
Publisher
Springer
Year
1994
Tongue
English
Weight
15 KB
Volume
20
Category
Article
ISSN
1572-9931

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Recombinant retroviral vectors are an attractive means of transferring genes into the liver because they integrate into the host cell genome and result in permanent gene expression. However, efficient in vivo gene transfer is limited by the requirement of active cell division for integration. Tradit