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Follistatin allows efficient retroviral-mediated gene transfer into rat liver

✍ Scribed by Josephine Borgnon; Fatima Djamouri; Isabelle Lorand; Virginie Di Rico; Nathalie Loux; Jean-Christophe Pages; Dominique Franco; Frédérique Capron; Anne Weber

Book ID
116289918
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
854 KB
Volume
328
Category
Article
ISSN
0006-291X

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Recombinant retroviral vectors are an attractive means of transferring genes into the liver because they integrate into the host cell genome and result in permanent gene expression. However, efficient in vivo gene transfer is limited by the requirement of active cell division for integration. Tradit