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Hepatic DNA adducts and production of mutagenic urine in 2,6-dinitrotoluene-treated B6C3F, male mice

✍ Scribed by S.Elizabeth George; Michael J. Kohan; Sarah H. Warren

Book ID
116123471
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
444 KB
Volume
102
Category
Article
ISSN
0304-3835

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## Abstract Acrylamide, a food contaminant, is carcinogenic in experimental animals, with both genotoxic and nongenotoxic pathways being proposed. To obtain information regarding mechanisms of acrylamide tumorigenesis, we compared the extent of DNA adduct formation and induction of micronuclei and