Heparin-induced thrombocytopenia and thrombosis as an under-diagnosed cause of flap failure in heparin-naive patients: A case report and systematic review of the literature
β Scribed by Tessler, Oren; Vorstenbosch, Joshua; Jones, Daniel; Lalonde, Sebastien; Zadeh, Teanoosh
- Book ID
- 126130114
- Publisher
- John Wiley and Sons
- Year
- 2013
- Tongue
- English
- Weight
- 81 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0738-1085
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## Abstract Heparinβinduced thrombocytopenia (HIT), which is characterized by thrombocytopenia and potentially serious thromboses, may develop in patients exposed to heparin anticoagulation. HIT is caused by antibodies to the heparin/platelet factor 4 (PF4) complex. Management of HIT involves disco
Heparin-induced thrombocytopenia and thrombosis syndrome (HITTS) is a severe complication of heparin caused by an antibody response to the heparin-platelet factor 4 complex which results in severe thrombosis. Heparin rechallenge in HllTS patients carries a high risk of inducing thrombosis. Antithrom