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Heparan sulfate proteoglycans and cancer

✍ Scribed by Blackhall, F. H. (author);Merry, C. L.R. (author);Davies, E. J. (author);Jayson, G. C. (author)

Book ID
111724617
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
77 KB
Volume
85
Category
Article
ISSN
0007-0920

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## Abstract Heparan sulfate proteoglycans (HSPGs), via their interactions with numerous effector molecules such as FGF‐2, IL‐8, and VEGF, regulate the biological activity of cells by acting as co‐receptors that promote signaling. The extent and nature of their role as co‐receptors is often misregul