## Abstract Endothelial cell (EC) migration is critical in wound healing and angiogenesis. Fluid shear stress due to blood flow plays an important role in EC migration. However, the role of EC surface heparan sulfate proteoglycans (HSPGs) in EC adhesion, migration, and mechanotransduction is not we
Multifunctionality of extracellular and cell surface heparan sulfate proteoglycans
โ Scribed by Catherine Kirn-Safran; Mary C. Farach-Carson; Daniel D. Carson
- Book ID
- 105758971
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 309 KB
- Volume
- 66
- Category
- Article
- ISSN
- 1420-682X
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A synthetic peptide, which was shown to bind extracellular matrix heparan sulfate chains with a high degree of affinity and specificity [Colburn et al. (1996): Arch Biochem Biophys 325:129-138], has now been found to promote the transfer and the deposition of endothelial cell surface proteoglycans i