Hemoglobin synthesis in BFU-E colonies derived from transfused blood in a sickle cell anemia patient

Synthesis of the minor fetal hemoglobin

Synthesis of the minor fetal hemoglobin Fic in colonies of erythropoietic precursors isolated from human umbilical cord blood

✍ E. C. Abraham; A. L. Reese; M. Stallings; A. Abraham; G. J. Garbutt; T. H. J. Hu 📂 Article 📅 1982 🏛 John Wiley and Sons 🌐 English ⚖ 385 KB

The biosynthesis of the minor hemoglobin F,c, which contains acetylated y chains, and the major hemoglobin F, was studied during erythroid cell differentiation and maturation in cultures of erythroid precursors isolated from five human umbilical cord blood samples. A gradual decrease in the synthesi