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Hemodynamic effects of dexmedetomidine in anesthetized dogs and their antagonism by ATP

โœ Scribed by J.W. Flacke; C.J. Lawrence; W.E. Flacke; F.W. Prinzen; M. Scheinin; S. de Lange


Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
123 KB
Volume
4
Category
Article
ISSN
0888-6296

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SK&F 85174 is a mixed DA-l/DA-2 receptor agonist which is shown to inhibit sympathetic neurotransmission and cause hypotension in anesthetized animals. In this study, we have determined the regional and systemic hemodynamic effects of an intravenous infusion of SK&F 85174 (5 pg/kg/min for 5 min) in