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Heme oxygenase-1 system, inflammation and ventilator-induced lung injury

✍ Scribed by Li An; Chang-Ting Liu; Min-Jun Yu; Zhen-Hong Chen; Xue-Guang Guo; Peng-Wang; Jun-Feng Wang; Xiang-Qun Fang; Yan-Hong Gao; Sen-Yang Yu

Book ID: 113589737
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 330 KB
Volume: 677
Category: Article
ISSN: 0014-2999
DOI: 10.1016/j.ejphar.2011.12.010

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Heme oxygenase-1 (HO-1) is a stress protein induced in response to a variety of oxidative challenges. After treatment of the hybrid septal cells SN 56 with ␤-amyloid peptide (␤-AP 1-40 ) or hydrogen peroxide (H 2 O 2 ), we detected high levels of reactive oxygen species, accompanied by a significant