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Heme oxygenase-1 attenuates the cisplatin-induced apoptosis of auditory cells via down-regulation of reactive oxygen species generation

✍ Scribed by Hyung-Jin Kim; Hong-Seob So; Jeong-Han Lee; Jae-Hyung Lee; Channy Park; Sung-Yeol Park; Yun-Ha Kim; Myung-Ja Youn; Se-Jin Kim; Sang-Young Chung; Kang-Min Lee; Raekil Park

Book ID
113629907
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
588 KB
Volume
40
Category
Article
ISSN
0891-5849

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## Abstract __N__‐(4‐hydroxyphenyl)retinamide (4HPR, fenretinide), a retinoic acid (RA) derivative and a potential cancer preventive agent, is known to exert its chemotherapeutic effects in cancer cells through induction of apoptosis. Earlier work from our laboratory has shown that relatively low c