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Simvastatin Inhibited the Apoptosis of PC12 Cells Induced by 1-Methyl-4-Phenylpyridinium Ion via Inhibiting Reactive Oxygen Species Production

✍ Scribed by Xu, Xudong; Gao, Wenming; Dou, Shanshan; Cheng, Baohua

Book ID: 118797585
Publisher: Springer
Year: 2012
Tongue: English
Weight: 369 KB
Volume: 33
Category: Article
ISSN: 0272-4340
DOI: 10.1007/s10571-012-9872-9

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## Abstract We reported previously that low levels of nitric oxide (NO) induced cell death with properties of apoptosis, including chromatin fragmentation and condensation in undifferentiated PC12 pheochromocytoma cells. The present study demonstrates that cytotoxicity of low concentrations of NO i