Heme endows human serum albumin (HSA) with globin-like reactivity and spectroscopic properties. Here, the effect of chlorpropamide, digitoxin, furosemide, indomethacin, phenylbutazone, sulfisoxazole, tolbutamide, and warfarin on peroxynitrite isomerization to NO 3 -by ferric HSA-heme (HSA-heme-Fe(II
✦ LIBER ✦
Heme impairs allosterically drug binding to human serum albumin Sudlow’s site I
✍ Scribed by Paolo Ascenzi; Alessio Bocedi; Stefania Notari; Enea Menegatti; Mauro Fasano
- Book ID
- 116290889
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 390 KB
- Volume
- 334
- Category
- Article
- ISSN
- 0006-291X
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