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Drug binding to sudlow's site i impairs allosterically human serum heme-albumin-catalyzed peroxynitrite detoxification, iubmb life 2010 oct;62(10):776–80

✍ Scribed by Paolo Ascenzi; Alessandro Bolli; Francesca Gullotta; Gabriella Fanali; Mauro Fasano


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
30 KB
Volume
63
Category
Article
ISSN
1521-6543

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✦ Synopsis


The authors wish to clarify the following information that was contained in their published article. They regret any confusion caused by the data as originally presented.

For graphical reasons,

While in the text and in Table 1 values of k on are correctly reported, derivation from slopes in Figure1 corresponds to k on 3 10.


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Drug binding to Sudlow's site I impairs
✍ Paolo Ascenzi; Alessandro Bolli; Francesca Gullotta; Gabriella Fanali; Mauro Fas 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 163 KB

Heme endows human serum albumin (HSA) with globin-like reactivity and spectroscopic properties. Here, the effect of chlorpropamide, digitoxin, furosemide, indomethacin, phenylbutazone, sulfisoxazole, tolbutamide, and warfarin on peroxynitrite isomerization to NO 3 -by ferric HSA-heme (HSA-heme-Fe(II