✦ LIBER ✦

Hematoporphyrin derivative photoradiation therapy

✍ Scribed by Michael W. Berns

Publisher: John Wiley and Sons
Year: 1984
Tongue: English
Weight: 175 KB
Volume: 4
Category: Article
ISSN: 0196-8092
DOI: 10.1002/lsm.1900040102

No coin nor oath required. For personal study only.

✦ Synopsis

The idea of using hematoporphyrin or hematoporphyrin derivative (HPD) in combination with light as a diagnostic and/or therapeutic modality for human cancer dates back to published work in the early 1960s. Lipson and Baldes [l] described the photodynamic properties of a hematoporphyrin derivative in the Archives of Dermatology in 1960. The same group similarly published hematoporphyrin cancer papers in 1961 [2], and 1972 [3]. Kelly and Snell described the potential use of HPD for bladder cancer diagnosis and treatment in 1976 [4].

However, as most investigators in this field will agree, the major impetus for the further growth and development of HPD-photoradiation therapy (PRT) in the treatment of human cancer has come from the work of T. J.

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