Hematological profile of sickle cell disease in central India
β Scribed by A. V. Shrikhande; A. A. Dani; J. R. Tijare; A. K. Agrawal
- Book ID
- 107645276
- Publisher
- Springer-Verlag
- Year
- 2007
- Tongue
- English
- Weight
- 98 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0971-4502
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Hematologic malignancy has rarely been reported in adults with sickle cell disease. We describe four sickle cell patients (two with hemoglobin SC, two with hemoglobin SS) who developed hematologic malignancy (acute myeloblastic leukemia, multiple myeloma, malignant histiocytosis, and Hodgkin's disea
The clinical and biological heterogeneity of sickle cell hemoglobin (Hb) C disease (SC disease) is similar to sickle cell anemia, but has a much milder course. The effect of genetic factors such as β£ thalassemia or β€-globin gene haplotype has been analyzed in a limited number of cases. In this work,