Helix Folding of an Alanine-Based Peptide in Explicit Water
β Scribed by Wu, Xiongwu; Wang, Shaomeng
- Book ID
- 126933508
- Publisher
- American Chemical Society
- Year
- 2001
- Tongue
- English
- Weight
- 355 KB
- Volume
- 105
- Category
- Article
- ISSN
- 0022-3654
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π SIMILAR VOLUMES
Thermal unfolding curves have been measured for a series of short alanine-based peptides that contain repeating sequences and varying chain lengths. Standard helix-coil theory successfully fits the observed transition curves, even for these short peptides. The results provide values for u, the helix
## Abstract A single aspartate residue has been placed at various positions in individual peptides for which the alanineβbased reference peptide is electrically neutral, and the helix contents of the peptides have been measured by circular dichroism. The dependence of peptide helix content on aspar