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Helicobacter pylori regulates p21WAF1 by histone H4 acetylation

โœ Scribed by Guoqing Xia; Regine Schneider-Stock; Antje Diestel; Caroline Habold; Sabine Krueger; Albert Roessner; Michael Naumann; Uwe Lendeckel

Book ID
116296473
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
396 KB
Volume
369
Category
Article
ISSN
0006-291X

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Acetylation of histones associated with the p21WAF1/CIP1 gene by butyrate is not sufficient for p21WAF1/CIP1 gene transcription in human colorectal adenocarcinoma cells
โœ Hanako Kobayashi; Er Mei Tan; Sharon E. Fleming ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 331 KB

## Abstract Butyric acid is well recognized as a histone deacetylase (HDAC) inhibitor, and changes in histone acetylation are thought to alter gene expression. The mechanism by which sodium butyrate (NaB) induces p21^WAF1/CIP1^, a critical gene involved in the antiproliferative effect of NaB, was s