Helical protein design
β Scribed by Christian E Schafmeister; Robert M Stroud
- Book ID
- 104362086
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 336 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0958-1669
No coin nor oath required. For personal study only.
β¦ Synopsis
It is now possible to design small proteins capable of folding into compact structures with well-packed cores. Given the present state of knowledge of protein folding and design, it is possible to extract a set of engineering guidelines that may assist in future de novo protein design.
π SIMILAR VOLUMES
Proteases play a key role in cellular biology and have become priority targets for new pharmaceuticals. Thus, there is a high demand for specific, sensitive, and quick assays to monitor the activity of endoproteases. We designed affinity-tagged helical proteins with unique protease cleavage sites an