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Hedgehog signalling as an antagonist of ageing and its associated diseases

✍ Scribed by Monireh Dashti; Maikel P. Peppelenbosch; Farhad Rezaee

Book ID
115550813
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
991 KB
Volume
34
Category
Article
ISSN
0265-9247

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## Abstract Cell differentiation and patterning are vital processes in the development of the appendicular skeleton. The hedgehog (Hh) signaling pathway plays a central role in regulating the anterior–posterior axis of the distal limb as well as the length of endochondral bones. Ligand‐induced Hh s