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Hedgehog promotes primary osteoblast differentiation and increases PTHrP mRNA expression and iPTHrP secretion

โœ Scribed by R Jemtland; P Divieti; K Lee; G.V Segre


Book ID
117807854
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
620 KB
Volume
32
Category
Article
ISSN
8756-3282

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We used both clonal osteoblast-like cells and primary calvarial osteoblastic cells to examine the role of Hedgehog in osteoblast biology. Primary osteoblasts and several clonal osteoblast-like cell lines express Indian hedgehog (Ihh), and genes encoding both components of its receptor, patched (Ptc)

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