We used both clonal osteoblast-like cells and primary calvarial osteoblastic cells to examine the role of Hedgehog in osteoblast biology. Primary osteoblasts and several clonal osteoblast-like cell lines express Indian hedgehog (Ihh), and genes encoding both components of its receptor, patched (Ptc)
Hedgehog promotes primary osteoblast differentiation and increases PTHrP mRNA expression and iPTHrP secretion
โ Scribed by R Jemtland; P Divieti; K Lee; G.V Segre
- Book ID
- 117807854
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 620 KB
- Volume
- 32
- Category
- Article
- ISSN
- 8756-3282
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