Heck reactions of amino acid building blocks: application to the synthesis of pyrrololine analogues

✍ Scribed by Philip N. Collier; Ian Patel; Richard J.K. Taylor

• Book ID: 104250931
• Publisher: Elsevier Science
• Year: 2002
• Tongue: French
• Weight: 125 KB
• Volume: 43
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(02)00512-9

✦ Synopsis

Heck reactions of unsaturated amino acid building blocks are described which allow access to homo-and bishomophenylalanine derivatives and to g,d-unsaturated amino acids. Preliminary synthetic studies utilising this chemistry for the preparation of pyrrololine and deoxypyrrololine analogues are also reported.