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Heck reactions in solid phase synthesis

✍ Scribed by Kuo-Long Yu; Milind S. Deshpande; Dolatrai M. Vyas


Book ID
103399942
Publisher
Elsevier Science
Year
1994
Tongue
French
Weight
236 KB
Volume
35
Category
Article
ISSN
0040-4039

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✍ J.Richard Morphy; Zoran Rankovic; Mark York πŸ“‚ Article πŸ“… 2002 πŸ› Elsevier Science 🌐 French βš– 77 KB

The use of extremely low solvent volumes (2 mL or less per mg resin) results in significant increases in yield for both the Diels-Alder and Heck reactions on solid-phase compared to standard high dilution techniques.