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Heavy-ion-induced bystander killing of human lung cancer cells: Role of gap junctional intercellular communication

โœ Scribed by Kosaku Harada; Tetsuo Nonaka; Nobuyuki Hamada; Hideyuki Sakurai; Masatoshi Hasegawa; Tomoo Funayama; Takehiko Kakizaki; Yasuhiko Kobayashi; Takashi Nakano

Book ID
108586419
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
220 KB
Volume
100
Category
Article
ISSN
1347-9032

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Vascular endothelial cells (EC), communicating with one another across gap junctions, are usually made dysfunctional by hypoxia and reoxygenation (H/R); however, very limited information exists regarding the effects of H/R on the endothelial gap junctions. We investigated whether H/R interferes with