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Heat-shocked Neuronal PC12 Cells Reveal Alzheimer's Disease—associated Alterations in Amyloid Precursor Protein and Tau

✍ Scribed by G. JOHNSON; L. M. REFOLO; W. WALLACE


Book ID
119868674
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
247 KB
Volume
695
Category
Article
ISSN
0890-6564

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One of the pathological lesions in Alzheimer's disease (AD) is the amyloid or senile plaque. The plaque core is predominantly made up of amyloid beta peptide (AP), a 42-43 amino acid peptide derived from amyloid precursor protein (APP). APP is a membrane bound glycoprotein which is expressed ubiquit