Heat Shock Response Inhibits NF-κB Activation and Cytokine Production in Murine Kupffer Cells
✍ Scribed by Dongxu Sun; Dechang Chen; Bin Du; Jiaqi Pan
- Book ID
- 116701912
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 243 KB
- Volume
- 129
- Category
- Article
- ISSN
- 0022-4804
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Recent studies suggest that sodium arsenite downregulates NF‐κB activity by inhibiting phosphorylation and subsequent degradation of IκBα. Many effects of sodium arsenite are secondary to induction of heat shock proteins. The role of the heat shock response in arsenite‐induced inhibitio
Upregulation of the phosphatidylinositol 3-kinase (PI3K)/Akt pathway has been described in some tumors related to multidrug resistance (MDR). The aim of this work was to analyze the relationship between PI3K/Akt, MDR and NF-kappaB in murine lymphoma cell lines resistant to vincristine (LBR-V160) and