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Telithromycin inhibits the production of proinflammatory mediators and the activation of NF-κB in in vitro-stimulated murine cells

✍ Scribed by Magdalena Leiva; Alfonso Ruiz-Bravo; Encarnación Moreno; Maria Jiménez-Valera

Book ID: 109309414
Publisher: John Wiley and Sons
Year: 2008
Tongue: English
Weight: 191 KB
Volume: 53
Category: Article
ISSN: 0928-8244
DOI: 10.1111/j.1574-695x.2008.00424.x

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## Abstract IL‐4 plays a pivotal role in the development of the Th2 cell mediated humoral immune response and causes IgE‐dependent allergic inflammatory diseases. Expression of IL‐4 in differentiated Th2 cells is regulated by transcription factors such as NF‐AT, AP‐1 and NF‐IL6. Recently, increasin