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Heat shock proteins alter in vivo abeta amyloid peptide aggregation

✍ Scribed by Maddelein, Marie-Lise; Reis, Suzanna Dos; Ramillon, Virginie; Bonzom, Cyrielle; Alami, Saad Mechiche


Book ID
120973197
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
77 KB
Volume
7
Category
Article
ISSN
1552-5260

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Heat shock alters Alzheimer's Ξ² amyloid
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One of the pathological lesions in Alzheimer's disease (AD) is the amyloid or senile plaque. The plaque core is predominantly made up of amyloid beta peptide (AP), a 42-43 amino acid peptide derived from amyloid precursor protein (APP). APP is a membrane bound glycoprotein which is expressed ubiquit