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Heat shock protein 104 inhibited the fibrillization of prion peptide 106–126 and disassembled prion peptide 106–126 fibrils in vitro

✍ Scribed by Ying-Hui Liu; Yan-Ling Han; Juan Song; Ying Wang; Yuan-Yuan Jing; Qi Shi; Chan Tian; Zhao-Yun Wang; Chao-Ping Li; Jun Han; Xiao-Ping Dong


Book ID
116308058
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
594 KB
Volume
43
Category
Article
ISSN
1357-2725

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✍ Ingrid Dupiereux; Willy Zorzi; Walid Rachidi; Danièle Zorzi; Olivier Pierard; Be 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 591 KB

## Abstract A synthetic peptide corresponding to the 106–126 amyloidogenic region of the cellular human prion protein (PrP^c^) is useful for in vitro study of prion‐induced neuronal cell death. The aim of the present work was to examine the implication of the cellular prion protein in the toxicity