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Heart allograft survival in rats following immunization with soluble peptide MHC class I donor antigens: evidence for the role of indirect recognition in rejection

โœ Scribed by Peter Terness; Christoph Dufter; Stefan Post; Jochen Thies; Gerd Otto; Tamer Koru; Gerhard Opelz


Book ID
115134457
Publisher
Springer
Year
1994
Tongue
English
Weight
168 KB
Volume
7
Category
Article
ISSN
0934-0874

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Allograft survival following immunizatio
โœ Peter Terness; Christoph Dufter; Gerd Otto; Gerhard Opelz ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Springer ๐ŸŒ English โš– 576 KB

T cells recognize foreign antigens in the form of peptide fragments resulting from antigen processing by antigen-presenting cells. In contrast to this indirect recognition, MHC molecules of foreign cells can be directly recognized by T cells. Direct recognition has for a long time been considered th