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Head to Tail Organization of the Human COL6A1 and COL6A2 Genes by Fiber-FISH

✍ Scribed by MERVI HEISKANEN; BIAGIO SAITTA; AARNO PALOTIE; MON-LI CHU


Book ID
115612860
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
79 KB
Volume
29
Category
Article
ISSN
0888-7543

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The COL6A1 and COL6A2 genes exist as a g
✍ Clair A. Francomano; Garry R. Cutting; Mary Kay McCormick; Mon Li Chu; Rupert Ti πŸ“‚ Article πŸ“… 1991 πŸ› Springer 🌐 English βš– 765 KB

The genes that encode the alpha 1 (VI) and alpha 2 (VI) collagen chains, designated COL6A1 and COL6A2, map to human chromosomal band 21q22.3. Using pulsed-field gel electrophoresis and somatic cell hybrids, we found that COL6A1 and COL6A2 form a gene cluster on the most distal part of chromosome 21.