๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Polymorphisms and linkage disequilibrium in the COL6A1 and COL6A2 gene cluster: novel DNA polymorphisms in the region of a candidate gene for congenital heart defects in Down's syndrome

โœ Scribed by G. E. Davies; C. M. Howard; L. M. Gorman; M. J. Farrer; A. J. Holland; R. Williamson; A. M. Kessling


Publisher
Springer
Year
1993
Tongue
English
Weight
665 KB
Volume
90
Category
Article
ISSN
0340-6717

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


The COL6A1 and COL6A2 genes exist as a g
โœ Clair A. Francomano; Garry R. Cutting; Mary Kay McCormick; Mon Li Chu; Rupert Ti ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Springer ๐ŸŒ English โš– 765 KB

The genes that encode the alpha 1 (VI) and alpha 2 (VI) collagen chains, designated COL6A1 and COL6A2, map to human chromosomal band 21q22.3. Using pulsed-field gel electrophoresis and somatic cell hybrids, we found that COL6A1 and COL6A2 form a gene cluster on the most distal part of chromosome 21.

Unusual genotypes in the COL6A1 gene in
โœ Gail E. Davies; Catherine M. Howard; Mathew J. Farrer; Michelle M. Coleman; Loui ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› Springer ๐ŸŒ English โš– 424 KB

Collagen type VI is a candidate for a role in the pathogenesis of congenital heart defects (CHD) in Down's syndrome. Three restriction fragment length polymorphisms of the COL6A1 gene were used to determine COL6A1 genotypes in 50 families of affected children with trisomy 21 (29 with congenital hear

Linkage disequilibrium analysis of polym
โœ Huang, Yi ;Li, Tao ;Wang, Yun ;Ansar, Jawaid ;Lanting, Guo ;Liu, Xiehe ;Zhao, Ji ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 66 KB ๐Ÿ‘ 2 views

## Abstract Gilles de la Tourette syndrome (GTS) is a neuropsychiatric disorder characterised by multiple motor and phonic tics, which wax and wane. Recently, evidence has accumulated supporting the role of autoimmune mechanisms in the aetiology of GTS, suggesting that it is within the paediatric a