Chronic hepatitis B virus (HBV) infection has a complicated course. Three phases are identified: an immune tolerant phase with high HBV DNA and normal alanine aminotransferase (ALT) levels associated with minimal liver disease; an immune active phase with high HBV DNA and elevated ALT levels with ac
Hbsag seroclearance in the natural history of chronic hepatitis b infection
β Scribed by Man-Fung Yuen; Ching-Lung Lai
- Book ID
- 107540441
- Publisher
- Current Science Inc.
- Year
- 2006
- Tongue
- English
- Weight
- 74 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1540-3416
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Seven patients are described in whom HBsAg persisted for 13 to 98 months after acute viral hepatitis B and then became nondetectable. All patients subsequently developed anti-HBs. During the period of HBs-antigenemia, liver biopsies in five patients showed persistent viral hepatitis. Retrospectively
## Abstract It have been suggested that hepatitis B virus (HBV) preβS deletions may play a role in hepatocarcinogenesis. The aim of the study was to determine the prevalence of preβS deletions in chronic hepatitis B patients in Hong Kong, the factors associated with the deletions and its relationsh