Seven patients are described in whom HBsAg persisted for 13 to 98 months after acute viral hepatitis B and then became nondetectable. All patients subsequently developed anti-HBs. During the period of HBs-antigenemia, liver biopsies in five patients showed persistent viral hepatitis. Retrospectively
HBsAg clearance in chronic active hepatitis B
โ Scribed by Timothy R. Morgan; Allan G. Redeker; Suyenori Yamada; Mary Ashcavai
- Book ID
- 112509135
- Publisher
- Springer US
- Year
- 1986
- Tongue
- English
- Weight
- 457 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0163-2116
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๐ SIMILAR VOLUMES
The natural history of chronic hepatitis B patients who spontaneously cleared serum HBsAg was investigated. A total of 351 patients with chronic hepatitis B were observed in our hospital for at least 3 yr. Seven of these patients became HBsAg negative during the follow-up period. HBsAg disappeared w
In this study, peripheral-blood mononuclear cells from patients with chronic hepatitis B and spontaneous or therapy-induced disappearance of HBsAg were examined for HBV DNA. Samples were evaluated by in situ hybridization and polymerase chain reaction both before and after clearance of HBsAg. By in