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Haplotype evolution of SLITRK1, a candidate gene for Gilles de la Tourette Syndrome

✍ Scribed by William C. Speed; Brian J. O'Roak; Zsanett Tárnok; Csaba Barta; Andrew J. Pakstis; Matthew W. State; Kenneth K. Kidd

Publisher: John Wiley and Sons
Year: 2008
Tongue: English
Weight: 162 KB
Volume: 147B
Category: Article
ISSN: 1552-4841
DOI: 10.1002/ajmg.b.30641

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## Abstract Numerous lines of evidence support the role of the catecholamines in the development of tics and Gilles de la Tourette syndrome (GTS). Dopamine‐β‐hydroxylase (DBH) is the key enzyme in the conversion of dopamine to norepinephrine and the alleles of several polymorphisms of the __DBH__ g