Specific chromosomal abnormalities of chromosomal region 6p21.3 have been described in subsets of many benign mesenchymal tumors. In the presented study, we investigated a series of 36 such cases by FISH, and Southern blot analyses for HMGIY rearrangements. FISH results revealed that the chromosomal
Hamartoma of the breast with involvement of 6p21 and rearrangement of HMGIY
β Scribed by Paola Dal Cin; Sylke Wanschura; Marie-Rose Christiaens; Ivo Van den Berghe; Philippe Moerman; Pietro Polito; Bernd Kazmierczak; Jorn Bullerdiek; Herman Van den Berghe
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 141 KB
- Volume
- 20
- Category
- Article
- ISSN
- 1045-2257
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β¦ Synopsis
The first description of involvement of 6p21 and rearrangement of HMGIY in a hamartoma of the breast is in keeping with the emerging role of HMG genes in benign mesenchymal tumors.
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