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Haloperidol – induced neurotoxicity – possible implications for tardive dyskinesia

✍ Scribed by R. Galili-Mosberg; I. Gil-Ad; A. Weizman; E. Melamed; D. Offen


Book ID
106208295
Publisher
Springer
Year
2000
Tongue
English
Weight
763 KB
Volume
107
Category
Article
ISSN
1435-1463

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## Abstract We describe a syndrome of spontaneous orofacial dyskinesias and cage stereotypies in a singly housed adult cynomolgus monkey never previously exposed to neuroleptic drugs. Abnormal movements were readily suppressed by acute treatment with haloperidol (0.03–0.24 mg/kg i.m.) or SCH23390 (