✦ LIBER ✦

Haloperidol facilitates memory retrieval in the rat

✍ Scribed by Susan J. Sara

Publisher: Springer
Year: 1986
Tongue: English
Weight: 432 KB
Volume: 89
Category: Article
ISSN: 0033-3158
DOI: 10.1007/bf00174365

No coin nor oath required. For personal study only.

✦ Synopsis

Rats were trained in a complex maze task for food reward. After a 25-day retention interval, they made more errors than at the last training trials. This forgetting was alleviated by pretest treatment with haloperidol. The same dose of haloperidol had no effect on acquisition or performance when injected during training. The results were replicated, but smaller doses were found to be inactive. The possibility that the effect might be mediated through the noradrenergic system is considered.

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