Haloperidol and reduced haloperidol plasma concentrations after a loading dose regimen with haloperidol decanoate
โ Scribed by Michael W. Jann; Fu-Chuan Weui; Hsin-Nan Lin; Ching Piao-Chien; Wen-Ho Chang
- Book ID
- 116120249
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 832 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0278-5846
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A single dose of haloperidol decanoate 100 mg was administered to 15 schizophrenic patients. Blood samples were obtained prior to injection, 1 h, 3 h, 6 h,'8 h, 1 day, 2 days, 3 days, 4 days, 5 days, 6 days, one week, two weeks, three weeks and four weeks post-injection. Haloperidol and its reduced
Plasma concentrations of haloperidol and its reduced metabolite (reduced haloperidol) were investigated in cigarette smokers (N = 23) and nonsmokers (N = 27). Steady-state plasma concentrations were obtained 12 h post bedtime dose. Haloperidol and reduced haloperidol concentrations were determined b