We analyzed whether normal human hepatocytes, which normally do not display Class I1 major histocompatibility complex antigens, can be induced to express them in vitro, and whether this induction has an in vivo counterpart in chronic liver diseases. While both a-and y-interferon induced expression o
Half-life of antigen/major histocompatibility complex class II complexes in vivo: intra- and interorgan variations
✍ Scribed by Klaus-Peter Müller; Jochen Schumacher; Bruno A. Kyewski
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 597 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0014-2980
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Besides their "classical" antigenic peptide-presenting activity, major histocompatibility complex (MHC) class II antigens can activate different cellular functions in immune and nonimmune cells. However, this "nonclassical" role and its functional consequences are still substantially overlooked. In
## DIEGO VERGANI' Controversy exists regarding major histocompatibility complex antigen expression on hepatocytes. In this study, hepatocyte expression of class I and I1 major histocompatibility complex antigens was investigated in diseased and normal livers, using indirect immunofluorescent stain