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Gαq-Dependent Activation of Mitogen-Activated Protein Kinase Kinase 4/c-Jun N-Terminal Kinase Cascade

✍ Scribed by Junji Yamauchi; Hiroshi Itoh; Hitomi Shinoura; Yuki Miyamoto; Keiko Tsumaya; Akira Hirasawa; Yoshito Kaziro; Gozoh Tsujimoto


Book ID
115588939
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
444 KB
Volume
288
Category
Article
ISSN
0006-291X

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Glial cells in the mammalian CNS are subject to environmental stress resulting from a variety of neuropathological conditions. In this study, we have examined the activation of a stress signal responsive kinase, i.e., stress-activated protein kinase (SAPK) or cJun N-terminal kinase (JNK), in primary