Gynecologic screening in hereditary nonpolyposis colorectal cancer
β Scribed by Fleur E.M Rijcken; Marian J.E Mourits; Jan H Kleibeuker; Harry Hollema; Ate G.J van der Zee
- Book ID
- 114101592
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 76 KB
- Volume
- 91
- Category
- Article
- ISSN
- 0090-8258
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π SIMILAR VOLUMES
Hereditary nonpolyposis colorectal cancer (HNPCC), or Lynch syndrome, is the most common form of hereditary colorectal cancer (CRC). A well-orchestrated cancer family history is essential for its diagnosis since, unlike its familial adenomatous polyposis (FAP) hereditary cancer counterpart, HNPCC la
Hereditary non-polyposis colorectal cancer (HNPCC) is an autosomal dominant disease, caused by germline mutations in DNA mismatch-repair genes (MMR). These mutations lead to microsatellite instability (MSI). It has been found that the MSI is not confined to the setting of hereditary disease and may